After years of research and studies, a revolutionary discovery has arrived in the medical field that could allow us to identify patients at risk for gastric cancer even before the disease presents itself
Our body receives, examines and sends millions of impulses every day. Among those it sends, there are important signals that concern our state of health. Precisely for this reason we must learn to understand and interpret these messages. Preventing or identifying a pathology early allows you to significantly increase the success rate of treatment and therefore recovery. However, many of these warning signs are very common and are therefore often confused and underestimated. Just like the symptoms that herald the stomach cancer. However, a turning point is coming in the medical field, in fact according to a new study it is possible to identify patients at risk by analyzing the bacteria present in the mouth.
Every year in Italy, on average, 78,000 new cases of tumors of the large intestinal tract, of which approximately 15,000 affect the stomach. Symptoms relating to stomach cancer, especially in the initial stages of the disease, are very common and can also be linked to other pathologies. Among the most recurring symptoms we find nausea, the feeling of fullness after meals even if small, digestive difficulties, pain and heartburn. Patients may also report vomiting or bloody stools. Given the presentation of this pathology, very often the diagnosis arrives when the tumor is already extensive. For this reason it screening and prevention are of fundamental importance.
However, a new test could change the general picture and the approach to the diagnosis of this pathology. According to a study presented at Digestive Disease Week (DDW) 2024, patients’ saliva, and its bacterial composition, could help identify patients at risk. According to the authors of the research, led by Dr Shruthi Reddy Peratiof the Rutgers Robert Wood Johnson School of Medicine in New Brunswick, i bacteria present in the mouth could provide a lot of information.
The study, carried out on 98 patients while awaiting gastroscopy, revealed some truly astonishing results. Of the 98 candidates, one third suffer from stomach cancer, one third from precancerous lesions such as ulcers or lesions and one third do not have any type of pathology which represent the control group. By analyzing the saliva and bacteria in the mouths of patients, researchers found some similar profiles among patients suffering from this pathology and substantial differences with the control group. 32 and 23 distinctly different bacterial genera were identified in the group with gastric cancer and the group with precancerous lesions.
Helicobacter, Selenomonas And Lectobacillus they are more abandoned in the groups with stomach cancer and lesions. Parabacteriodes genera were more abundant in healthy subjects, Alistipes And Phascolarctobacterium.
“Through this type of analysis, using a simple mouthwash for sample collection, we are able to identify biomarkers that may be related to gastric cancer risk. As a screening and prevention tool, it would be the ideal solution. Early diagnosis in cancer is certainly critical, but if we can detect patients before they develop the disease, we may be able to prevent it.”
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A revolutionary discovery that could change the lives of many people. It is essential to remember that the prevention and medical check-ups can help prevent or early identify many types of disease, not just cancer.
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awesome