A group of researchers from the University of Granada (UGR) discovered this week The therapeutic properties of a natural compound to treat obesity and steatotic disease closely linked to metabolic dysfunction (MASLD).
It is about the b-resorcylic acidwhich is found in certain foods, especially berries and black olives. In oral supplementation administered in the diet, leads to considerable weight loss.
Step by step
The study, led by researchers from the UGR and with international participation, has been published in ‘BBA – Molecular bases of disease’. Apparently, experts have revealed that oral supplementation with a small molecule of phenolic character administered through diet leads to substantial weight loss in a murine model of diet-induced obesity.
“The decrease in weight is due to the loss of fat mass, without affecting muscle mass content.“He explained forcefully Maria Elena Diazresearcher at the Biomedical Research Center and who has participated in this work.
More details
The anti-obesity effects of this molecule have been detailed through a combination of the normalization of mitochondrial metabolism of coenzyme W in white adipose tissue and the activation of lipid metabolism in the liver, increasing beta-oxidation and triglyceride degradation.
“Consequently, oral supplementation with this phenolic compound prevents and reduces the accumulation of white fat, prevents liver steatosis and also improves homeostasis of glucose by reducing insulin resistance and plasma levels of gastric inhibitory peptide (GIP),” argued Elena Diaz Casadoresearcher at the Department of Physiology.
Future
With all this, the UGR has taken a step giant‘in search of alternatives natural and effective against obesity, a growing problem worldwide. So far, you have treatment options with several Efficacy Limitations and Side Effects.
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