Police added that the driver of the vehicle, whom they described as a suspect, was “immediately neutralized”.
The Israeli Ambulance Service said it was treating three people who were injured, including a 50-year-old man who was unconscious and in serious condition.
Local television stations showed footage showing a heavy police presence at the scene near a crowded market in Jerusalem.
Israeli Prime Minister Benjamin Netanyahu described it as a “terrorist attack”.
He added: “This reminds us once again that Israel always faces danger and will not hesitate to repel it.”
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