A new anti-aging drug has proven effective in mice, presenting fewer side effects compared to conventional ones. This drug blocks a key protein in glucose transport, offering potential benefits against age-related diseases, such as diabetes and atherosclerosis, and extending lifespan. The discovery, published on Nature Agingwas carried out by researchers at Juntendo University in Japan.
Cellular aging, or cellular senescence, is a process in which cells stop dividing but do not die, contributing to age-related diseases. Many anti-aging treatments aim to eliminate these cells, but are often accompanied by serious side effects. The new drug, called canagliflozinalready used for type 2 diabetes, shows significant potential in reducing these side effects.
New anti-aging drug: the results of the study
The researchers, coordinated by Tohru Minamino, conducted experiments on obese mice, observing an improvement in glucose metabolism, a reduction in inflammation in adipose tissue and a significant reduction in senescent cells. All this with far fewer side effects than other drugs. Minamino said:
“We have demonstrated an improvement against diabetes, atherosclerosis, premature aging and frailty, as well as an extension of lifespan thanks to the inhibition of the glucose transporter SGLT2.”
According to the researchers, the drug could also be used in the future to treat neurodegenerative diseases such as Alzheimer’s disease. This opens up new perspectives in fight against age-related diseases and could significantly improve the quality of life in older people.
What do you think of these new discoveries? Do you think they can revolutionize the treatment of age-related diseases?
#antiaging #drug #effective #mice #side #effects #benefits
