An innovative development by researchers at the Institute of Cancer Research London and the Royal Marsden NHS Foundation Trust could forever change the way prostate cancer is detected. This is a saliva test that promises to revolutionize early detectionidentifying high-risk patients and reducing unnecessary treatments.
The saliva test, based on the extraction of DNA through a simple sample, has proven to be superior to traditional methods such as PSAwhich often miss cancer cases or lead to unnecessary treatments.
Conclusive results that save lives. The findings, which will be presented at the world’s largest cancer conference, indicate that The saliva test detects a higher proportion of aggressive cancers and significantly reduces false positives.
The Barcode 1 trial, with more than 6,000 European participants, used the test to calculate the polygenic risk score (PRS) based on 130 genetic variations associated with prostate cancer.
The test identified cases that would have been missed by the PSA test and was also able to detect cancers not revealed by MRIs.
Dheeresh Turnbull, one of the first participants in the trial, discovered that he had prostate cancer thanks to the saliva test. This allowed for an early diagnosis and successful surgery, saving his life.
However, the investigation continues. More studies are needed to ensure the test benefits men in all populations.
The future of prostate cancer diagnosis is here. With cases projected to increase by 2040, the need for early and accurate diagnosis is more urgent than ever. This saliva test represents a significant advance towards improving detection and treatment methods for this disease.
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