Investigate the safety and efficacy of vaccination against SARS-CoV-2 During pregnancy it has become necessary. Now, a team of American scientists has detected a type of antibodies against covid-19 in umbilical cord bloodl of a newborn after maternal vaccination.
This is, according to scientists from Florida Atlantic University, the first known reported case of an infant with IgG immunoglobulins, one of the five antibodies that the body makes to defend itself against pathogens and that are linked to SARS-CoV-2.
It is, according to scientists at Florida Atlantic University, the first known reported case of an infant with IgG immunoglobulins (DPA).
This is a preliminary study published in medRxiv, a repository of scientific articles whose conclusions have not been verified by independent researchers (peer review).
The signatories of this new work recall that there is an important and urgent need to investigate the safety and efficacy of vaccination against SARS-CoV-2 during pregnancy.
Maternal vaccination against influenza and TDaP (tetanus, diphtheria, pertussis) has been well studied both in terms of safety and efficacy for the protection of the newborn through the passage of antibodies through the placenta, so one would expect (says the study) similar protection after the mother received the vaccine against SARS-CoV-2, the covid-19 virus.
The vaccine was given to a first-line health worker, 36 weeks and 3 days pregnant; delivery (vaginal) was normal and spontaneous three weeks after the first dose of the covid vaccine (Photo: Pixabay)
The vaccine (in this case Moderna’s) was provided to a frontline health worker, with a pregnancy of 36 weeks and 3 days; delivery (vaginal) was normal and spontaneous three weeks after the first dose of the covid vaccine.
A healthy girl was born, with a normal evolution, to which several samples of blood of the umbilical cord were taken; the serum was sent to the laboratory for coronavirus antibody testing.
Meanwhile, the mother received the second dose of the Moderna vaccine according to the normal schedule of the 28-day vaccination protocol.
The results showed the detection of IgG antibodies in the umbilical cord blood against the S protein of SARS-CoV-2 (the protein that the coronavirus uses to enter human cells).
A team of American scientists has detected a type of antibodies against COVID-19 in the umbilical cord blood of a newborn after maternal vaccination (APD).
“We have shown that SARS-CoV-2 IgG antibodies are detectable in umbilical cord blood sample from a newborn after a single dose of the vaccine“, point out the scientists, who point out that although it is a single case, there is therefore the possibility of protection and reduction of the risk of infection by SARS-CoV-2 with maternal vaccination.
However, the protective efficacy in newborns and infants is still unknown. the ideal time for maternal vaccination; For example, more studies are needed to quantify the amount and duration of viral neutralizing antibodies present in babies.