Between 27 December 2020 and 26 July 2021 for the four vaccines in use in the current vaccination campaign, 84,322 reports were received out of a total of 65,926,591 doses administered (reporting rate of 128 per 100,000 doses), of which 87 , 1% referred to non-serious events, such as injection site pain, fever, asthenia / fatigue, muscle aches. Serious reports are 12.8% of the total, with a rate of 16 serious events per 100,000 doses administered.
These are the data that emerged from the seventh AIFA Report on the surveillance of Covid-19 vaccines. The reactions occurred in about 80% of cases on the same day of vaccination or the following day and only more rarely beyond the following 48 hours. Then, add the Aifa experts, ‘most of the reports are related to the Pfizer vaccine (68%), the most used in the vaccination campaign (71% of the doses administered) and only to a lesser extent to AstraZeneca (25% of the reports and 17 % of doses administered), Moderna (6% of reports and 10% of doses administered) and Covid-19 J&J (1% of reports and 2% of doses administered). For all vaccines, the most reported adverse events are fever, fatigue, headache, muscle / joint pain, injection site pain, chills and nausea.
The most frequently reported vaccination-related serious adverse events are a flu-like syndrome with intense symptoms, more frequent after the second dose of mRna vaccines and after the first dose of AstraZeneca. As for “heterologous” vaccinations for under 60s, 114 reports were received out of a total of 396,952 administrations (the second dose involved 82.6% of Pfizer cases and 17.4% Moderna), with a reporting rate of 29 for every 100,000 doses administered. In the 12-19 age group, the distribution by type of adverse events’ is not substantially different from that observed for other ages ”.