He Miler Fisher Syndrome (SMF) It is a variety of Guillain Barrè syndrome and presents as main characteristics:
– Oculomotor system disorder that prevents voluntarily from moving the eyeball (ophthalmoplejía).
– Lack of muscle control or coordination of voluntary movements (ataxia).
– Absence of reflexes (Reflexia).
It is generally associated with respiratory or digestive infections. This autoimmune disease generates serious movements coordination problems and with proper treatment has a cure.
Guillain-Barré syndrome, which is a variant, is a set of diseases that occur because of various infections that cause a malfunction of the immune system such as Epstein-Barr virus, ‘Salmonella Enteritidis’, ‘Chlamydia pneumoniae’ and ‘Mycoplasma pneumoniae’. Miller Fisher syndrome usually has a cure and the symptoms disappear. But sometimes there are sequelae in the nervous system. It is estimated that there is more or less twice as many cases of Miller Fisher syndrome in women than in men.
Miller Fisher Syndrome Causes
Infections
The reason why this disease develops is not clear 100%. It seems clear that the most likely cause is viral or bacterial infection, but it is not ruled out that there are other causes. Symptoms occur because the immune system destroys the myelin of peripheral nerves. Myelin collaborates in the transmission of nerve impulses and its destruction causes problems in the central nervous system. It has also been shown that the Immunoglobulin antibody antiganglióside GBQ1B is in most people with the diagnosis of Miller Fisher syndrome. This antibody is associated with ophthalmoplegia.
Miller Fisher syndrome symptoms
Three symptoms that are repeated
The so-called triad of usual signs that are always associated with Miller Fisher syndrome and differentiates it from other types of Guillain-Barré syndrome: ataxia, grieflexia and ophthalmoplegia. They are symptoms that appear between 5 and 10 days after having the infection.
Ophthalmoplegia and ataxia are frequently the first signs of the disease. Ophthalmopling entails the paralysis of the muscles of the eyeball. Ataxia is the loss of motor coordination. Reflexia is the absence of reflex movements.
Other symptoms are the problems in cranial nerves, muscle weakness and respiratory problems, which even in the most extreme case can lead to death if the symptoms are very intense. However, these complications are more common in other forms of Guillain-Barré syndrome.
Miller Fisher Syndrome Diagnosis
VISUAL ANALYSIS AND EXAM
The doctor should study the clinical history, perform a visual examination of the symptoms and perform various analysis and diagnostic tests by image.
Treatment and medication of Miller Fisher Syndrome
Two techniques
As in the other variants of Guillain-Barré syndrome, Miller Fisher’s ailment is treated through two techniques: plasmapheresis, which means eliminating antibodies from the blood by filtration, and the administration of immunoglobulins intravenously. The objective of these treatments is to combat the effects of pathological antibodies and to reduce swelling in some areas and accelerate recovery.
In most cases, the patient takes between two weeks and a month to feel that he begins to recover. At six months, normal is already having very few symptoms and very slight.
Miller Fisher syndrome prevention
There is no prevention
The most likely cause of this disease is infection, but it is very difficult to prevent a person from suffering from infections at some point in his life. And obviously only in very few cases the infection leads to develop Miller Fisher syndrome.
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