Experts discussing this rare pathology. Brussino, “The diagnosis involves the examination of organ involvement even in the absence of characteristic symptoms affecting that organ. It is therefore a diagnosis of exclusion, which requires time and attention, on the one hand to define the cause of hypereosinophilia and on the other to define the extent of organ involvement. For this reason it is essential to create multidisciplinary teams that collaborate for the purpose of a correct diagnostic and management approach to this disease”. Papayannidis, “The haematologist also plays a key role: from a diagnostic point of view, the haematologist must first exclude those that are clonal bone marrow pathologies caused by the presence of genomic rearrangements or alterations that determine an abnormal proliferation of eosinophils; where there is no cause found, then we will talk about idiopathic forms, for which today we have a new drug available, an antibody, which acts against an interleukin, interleukin 5. This antibody is called mepolizumab and it has the ability to modify and improve the symptoms that these patients may present, consequently improving their quality of life.”
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