To modulate the inflammation caused by endurance activity, “the combination of maltodextrin and fructose in a 2:1 ratio is useful, as demonstrated in the study presented today and conducted by the Enervit team”, which highlights “how the levels of interleukin-6 and cortisol were significantly lower among the athletes involved in the study who had taken the combination of maltodextrin and fructose compared to those who had taken the placebo”. As Stefano Righetticardiologist at the S.Gerardo hospital in Monza, on the occasion of the panel ‘Physical activity and exercise for healthy longevity’ which today opened the second day ofthe V International Congress “Healthy lifespan – positive nutrition, antiinflammation diet, physical activity and sport” organized by the Paolo Sorbini Foundation, and promoted by Enervit and Technogym, at Palazzo Mezzanotte in Milan.
At the center of Righetti’s speech is the management of inflammation in resistance exercise. “Moderate physical activity has an inflammation-reducing effect compared to a sedentary lifestyle – explains the expert – However, the case of high-intensity endurance exercise is different. Intense sport causes an increase in inflammatory cells in the blood The factors that influence inflammation in endurance sport are mainly the duration of the activity and the intensity, as well as recovery. The mechanisms associated with inflammation are those of energy metabolism, muscle and tissue adaptation, and recovery post exercise and also iron absorption”.
“Interleukin 6 (Il-6), an inflammatory molecule, can increase up to 100 times after extreme physical effort – underlines the cardiologist – When glycogen levels in the muscles are reduced, the production of interleukin 6 increases, leading to the release of free fatty acids which are used to produce energy. After intense exercise, there is muscle damage which leads to the release of calcium, which in turn activates local inflammation in the muscle it becomes systemic as the hours pass and the athlete experiences muscle pain, increased protein turnover and increased muscle volume. After the activation of post-exercise inflammation, molecules that modulate inflammation are also activated, thus allowing regeneration and tissue repair”. After 12-24 hours of the acute phase of inflammation, the chronic phase takes over, “during which if interleukin 6 remains high there is a reduction in muscle strength and an increase in muscle pain – adds Righetti – Furthermore, physical activity intense activity leads to a reduction in the efficiency of the immune system for a few hours. Iron absorption is affected by high levels of inflammation caused by intense endurance physical exercise.” Omega 6 “are molecules that contribute to activating inflammation, on the contrary Omega 3 reduce it. Phospholipases are able to detach Omega 3 and Omega 6 from the cell membrane and therefore manage the mechanisms of activation and deactivation of inflammation “, he concludes.
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