Pfizer will seek authorization from US regulators to a third dose of your coronavirus vaccine since, according to the pharmacist, another injection within 12 months could dramatically increase immunity and perhaps it would provide protection against the new, more contagious variants of the virus.
Research in several countries shows that Pfizer injection and other widely used covid-19 vaccines deliver strong protection against the Delta variant, which is more contagious and is spreading rapidly around the world. In Argentina it was detected in 7 cases, all imported.
Two doses of most vaccines are critical for developing high levels of antibodies against all versions of the coronavirus, not just the Delta variant (first detected in India). But in much of the world, the first dose has yet to be received or the second is delayed as the pandemic continues.
Antibodies naturally decline over time, so studies are also underway to determine if and when boosters may be needed.
“The companies hope to publish more definitive data soon, as well as in a peer-reviewed journal, and plan to send the data to the FDA (of the United States), the EMA (of Europe) and other regulatory authorities in the coming weeks,” the Pfizer and BioNTech laboratories indicated in a joint statement.
Pfizer’s Dr. Mikael Dolsten told AP on Thursday that early data from the company’s booster study indicates that a person’s antibodies increase five to 10 times after a third dose, compared to a second injection months before.
Pfizer plans to apply to the US Food and Drug Administration (FDA) for emergency authorization of a third dose in August, the doctor said.
Why is this important for the Delta variant? Dolsten pointed to data from Britain and Israel showing that Pfizer’s vaccine “neutralizes very well” this variant. The assumption, he said, is that when the antibodies get low enough, the Delta variant could cause a mild infection before the immune system kicks in again.
FDA clearance would only be a first step; would not automatically mean that people are offered reinforcementswarned Dr. William Schaffner, a vaccine expert at Vanderbilt University Medical Center.
Public health authorities would have to decide if they are really necessaryespecially since millions of people have no protection.
“The vaccines were designed to keep us out of the hospital,” and continue to do so despite the delta variant, he said. Giving another dose would be “a big effort while we’re still trying to get people to get the first dose.”
Source: AP and AFP