Paxlovid has “conditional marketing authorisation” for Europe. The corona drug has not only provided positive data in studies.
Since the end of January 2022, Paxlovid received “conditional marketing authorisation” from the European Medicines Agency (EMA). After there were initially problems with the delivery for Germany, that is Corona drug from the manufacturer Pfizer has been available in Germany since February 23.
In addition to positive studies and a Comparison with the drug molnupiravir from Merck & Co., Recently, critical voices about Paxlovid have also been reported. There was always talk of possible ones Interactions with other drugs. Experts have even created a “red” list.
Paxlovid: First corona drug for the home
According to doctors, Paxlovid is the first corona drug for home use. The preparation from Pfizer is taken in tablet form and is used to prevent severe courses. echo24.de reports on this.
Conditional Authorization (CMA)
According to EMA’s official statement, conditional authorization (CMA) is used as an accelerated authorization process to speed up the approval of medicines in public health emergencies in the EU. CMAs allow for the approval of medicines that address an unmet medical need based on less complete data than would normally be required. This happens when the benefit of having a medicine readily available to patients outweighs the risk of not having all the data yet.
Especially since Paxlovid can also be taken at home, it is important to know some crucial information about the US manufacturer’s corona pill.
Use and effect of Paxlovid
how echo24.de As reported in earlier articles, Paxlovid is a combination therapy. It involves two key oral antiviral agents. The Pharmazeutische Zeitung, among others, wrote about the substances used: “It is the new substance PF-07321332 developed by Pfizer, now called nirmatrelvir, which inhibits the viral protease 3CL, which is important for the multiplication of SARS-CoV-2, and on the other hand the well-known ritonavir, which acts as a booster by inhibiting the Breakdown of nirmatrelvir via CYP3A4 in the liver slows down”.
According to the manufacturer and numerous experts, taking Paxlovid must begin no later than five days after the onset of symptoms – and then for five days. The corona drug is by no means a miracle cure. Opposite of German Press Agency (dpa) The German Society for General and Family Medicine (DEGAM) explained a few days ago: “Paxlovid is not the pandemic survivor, but the vaccination.” Paxlovid is therefore rather a “emergency nail”.
Paxlovid: For whom does the corona drug make sense at all
In the dpa report, DEGAM also made it clear that the use “extreme caution and good patient education and monitoring” require. The area of application of Paxlovid is also limited. Professionals hold an application “for the unvaccinated over 65s who have not yet recovered” for reasonable.
Various studies have shown that Pfizer’s preparation is considered to be very suitable for patients who are not vaccinated and have at least one risk factor. Stefan Kluge, intensive care physician and expert from the German Society for Pneumology and Respiratory Medicine (DGP), explained to the dpa: “Based on previous data, it is not a drug for, for example, slim, athletic 20-year-olds or 60-year-olds with a booster who receive a positive test result .”
So far, there is no reliable data on use in vaccinated people in general. And there is still no proof of effectiveness against the omicron variant of Corona. The data for approval by the EMA predates Omicron. However, the researchers assume protection against this variant. On the other hand, molnupiravir has already delivered an omicron study.
Paxlovid available in pharmacies – this is how patients get the corona drug
As soon as it became clear that deliveries to Germany should start in February, there were first indications for patients how they could get Paxlovid. As the dpa reports, Professor Kluge from the University Hospital Hamburg-Eppendorf also pointed out the problem of timely treatment in this regard.
Many patients could not go to the doctor immediately. In addition, it would then take some time before the test result was available. The Federal Union of German Associations of Pharmacists stipulates that, as an exception, doctors should send prescriptions directly to pharmacies, which then order the drug from wholesalers and receive it “as little contact as possible” deliver to patients by messenger. Pharmacies are not allowed to stock Paxlovid.
Pfizer with Paxlovid in the fight against Corona the winner in the billion dollar business
For the US pharmaceutical company Pfizer, Paxlovid is another top-selling drug in the fight against Corona. The manufacturer has already achieved good results with the vaccine Biontech at the beginning of the vaccination campaign. The company is considered the big winner of the pandemic in the billion dollar business of pharmaceutical manufacturers. *echo24.de is an offer from IPPEN.MEDIA
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