The former PSV player kept his hamstring injury from the lost game against Bayern Munich in the Champions League at the beginning of December (3-0). The striker made his comeback after a month, but after two substitutions he suffered again.
Barcelona recorded convincing victories last week at Valencia (1-4) and in the Europa League at Napoli (2-4). The team of trainer Xavi is in fourth place in La Liga. Last month, Barcelona was eliminated by Athletic (3-2) in the Spanish cup tournament after extra time.
Frenkie de Jong, Luuk de Jong and Sergiño Dest are also part of the selection for the duel with the Basques.
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