In a new study from the University of California at San Diego School of Medicine, researchers found that patients who take medications with statins, commonly used to lower blood cholesterol levels, have a 41 percent lower risk of death in their lifetime. hospital due to Covid-19.
Using data from the American Heart Association Registry of Cardiovascular Diseases, the team analyzed the medical records of 10,541 patients hospitalized by Covid-19 during the period January-September 2020 at 104 different hospitals.
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Lori Daniels, professor and director of the Cardiovascular Intensive Care Unit at UC San Diego and lead author of the study, said that early in the pandemic there was a lot of speculation surrounding certain drugs that affect the body’s ACE2 receptor, including statins, and whether they may influence the risk of Covid-19.
“At the time, we thought that statins could inhibit SARS-CoV-2 infection through their known anti-inflammatory effects and binding capabilities, which could potentially halt the progression of the virus,” she said.
We performed more advanced analyzes as they tried to control for coexisting medical conditions, socioeconomic status, and hospital factors. “By doing this, we confirm our previous findings that statins are associated with a reduced risk of death among patients hospitalized for Covid-19.”
“We matched each patient with one or more similar patients, using the hospital’s website, month of admission, age, race, ethnicity, gender, and a list of pre-existing conditions, in order to make the two groups as comparable as possible. ,” added Karen Messer, study co-author and professor of biostatistics at the University of San Diego.
The person responsible for the study reported that the benefit of statins was found mainly in patients who use the drug for medical reasons, such as cardiovascular disease and hypertension. In this group, 32% of patients with Covid-19 had a lower risk of death.
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