Alternative gene scissors: Based on the red color on the culture plate, the brain employee recognizes whether the genome editing was successful.
Image: Brain Biotech
Enzyme specialist Brain Biotech is now involved in the billion-dollar market for revolutionary genetic engineering CRISPR / Cas. The company was able to prove that the gene scissors worked with the help of a mold from the bathroom.
E.in cloudy pools by the wayside. A forest pond. A pond in Cologne. Standing, stinking waters, full of algae, creepers and mysterious air bubbles that rise and burst on the surface – is the future of genetic research to be found here? Michael Krohn certainly thinks so. From around 30 such bodies of water, which he calls habitats, he and his research colleagues from the Zwingenberg biotech company Brain have skimmed around 20 liters each. “We even wanted the water from zoo aquariums, but the zookeepers didn’t find that strange at all,” says Krohn.
The head of research at Brain and his team are looking for phages, viruses that infect bacteria. And that happens particularly often in such pools. This search is not exactly difficult, in one liter of pool water, explains Krohn, ten billion phages can be found. The brain researchers analyzed and sequenced the genomes of bacteria from these habitats, and in the end they recorded 100 million genes, a data volume of two terabytes. If printed out, that would add up to five million books.